County-level vaccination coverage and rates of COVID-19 cases and deaths in the United States: An ecological analysis.

ABSTRACT:

Background

On Dec 14, 2020, the United States initiated a nationwide COVID-19 vaccination campaign. Demonstrating clear population-level impact following vaccine introduction helps to further elucidate and quantify the public-health benefits of vaccination.

Methods

Using a negative binomial regression model we evaluated the ecological association between county-level COVID-19 vaccine uptake and rates of COVID-19 cases and deaths in the United States from April 1, 2021 through October 31, 2021 controlling for a broad set of county-level environmental, sociodemographic, economic, and health-status-related characteristics. County-level data were obtained from several publicly available databases that were merged for analysis.

Findings

After adjustment for county-level ch

SUBMITTER: McLaughlin JM 

PROVIDER: S-EPMC8802692 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature