Genome-wide insights into adaptive hybridisation across the Schistosoma haematobium group in West and Central Africa.

ABSTRACT: Schistosomiasis remains a public health concern across sub-Saharan Africa; current control programmes rely on accurate mapping and high mass drug administration (MDA) coverage to attempt disease elimination. Inter-species hybridisation can occur between certain species, changing epidemiological dynamics within endemic regions, which has the potential to confound control interventions. The impact of hybridisation on disease dynamics is well illustrated in areas of Cameroon where urogenital schistosomiasis, primarily due to Schistosoma haematobium and hybrid infections, now predominate over intestinal schistosomiasis caused by Schistosoma guineensis. Genetic markers have shown the ability to identify hybrids, however the underlying genomic architecture of divergence and introgression between

SUBMITTER: Landeryou T 

PROVIDER: S-EPMC8803156 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature