Insulin-induced Lipohypertrophy in Patients with Type 1 Diabetes Mellitus Treated with an Insulin Pump.

ABSTRACT:

Background

Lipohypertrophy (LH) of subcutaneous tissue is an insulin-induced complication occurring in patients with diabetes. We aimed to define the prevalence of LH and identify its risk factors in type 1 diabetes (T1DM) patients treated with continuous subcutaneous insulin infusion (CSII).

Materials and methods

The study included 79 consecutive CSII-treated T1DM patients. The diagnose of LH was based on ultrasonography (US) as a reference method, physical examination was also performed. Clinical characteristics were available from the medical records.

Results

The median age of patients was 28 years (interquartile range [IQR], 24-30.5) with a body mass index (BMI) of 24.5 ± 3.5 kg/m², HbA_1c 7.1% (IQR, 6.7-8.1), T1DM duration 15 (9-20) years, an

SUBMITTER: Ucieklak D 

PROVIDER: S-EPMC8803446 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature