Menstrual cycle characteristics and incident cancer: a prospective cohort study.

ABSTRACT:

Study question

Are menstrual cycle characteristics throughout the reproductive lifespan associated with cancer risk?

Summary answer

Irregular and long menstrual cycles throughout the reproductive lifespan were associated with increased risk of total invasive cancer, especially obesity-related cancers.

What is known already

Long and irregular menstrual cycles have been associated with lower risk of pre-menopausal breast cancer and higher risk of endometrial cancer, but associations with other malignancies are less clear.

Study design, size, duration

Prospective cohort study. Prospective follow-up of 78 943 women participating in the Nurses' Health Study II between 1989 and 2015.

Participants/materials, setting, methods

We followed 78 943 pre-menopausal wo

SUBMITTER: Wang S 

PROVIDER: S-EPMC8804333 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature