Health State Utilities for Sickle Cell Disease: A Catalog Prepared From a Systematic Review.

ABSTRACT:

Objectives

Sickle cell disease (SCD) is a complex, chronic condition that impairs health-related quality of life of affected individuals and their caregivers. As curative therapies emerge, comprehensive cost-effectiveness models will inform their value. These models will require descriptions of health states and their corresponding utility values that accurately reflect health-related quality of life over the disease trajectory. The objectives of this systematic review were to develop a catalog of health state utility (HSU) values for SCD, identify research gaps, and provide future directions for preference elicitation.

Methods

Records were identified through searches of PubMed and Embase, Tufts Medical Center Cost-Effectiveness Analysis Registry, reference lists of relevant

SUBMITTER: Jiao B 

PROVIDER: S-EPMC8804335 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature