Resorbable Pins to Enhance Scaffold Retention in a Porcine Chondral Defect Model.

ABSTRACT:

Objective

Cartilage repair strategies have seen improvement in recent years, especially with the use of scaffolds that serve as a template for cartilage formation. However, current fixation strategies are inconsistent with regards to retention, may be technically challenging, or may damage adjacent tissues or the implant itself. Therefore, the goal of this study was to evaluate the retention and repair potential of cartilage scaffolds fixed with an easy-to-implement bioresorbable pin.

Design

Electrospun hyaluronic acid scaffolds were implanted into trochlear groove defects in 3 juvenile and 3 adult pigs to evaluate short-term retention (2 weeks; pin fixation vs. press-fit and fibrin fixation) and long-term repair (8 months; scaffold vs. microfracture), respectively.

Resul

SUBMITTER: Patel JM 

PROVIDER: S-EPMC8804863 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature