Breastfeeding moderates the relationship between fat mass and obesity-associated gene rs9939609 and body mass index among adolescents.

ABSTRACT:

Objective

Breastfeeding, which is important for early growth, is a possible moderator of genetic influence, such as the effect of the fat mass and obesity-associated gene (FTO) on body mass index (BMI). The aim of this study was to assess the moderating effect of breastfeeding duration on the relationship between FTO rs9939609 and BMI in a Caucasian sample.

Methods

Adolescents born in 1997 and in 1999, who were living in the Swedish county Västmanland in 2012, were invited to participate in the Survey of Adolescent Life in Västmanland. The adolescents and their parents completed self-reported questionnaires in 2012, 2015, and 2018. Genotyping of rs9939609 T > A polymorphism was conducted from saliva DNA samples. Interaction effects of parental reported breastfeeding d

SUBMITTER: Kanders SH 

PROVIDER: S-EPMC8804930 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature