Comparative metabolomic analysis reveals shared and unique chemical interactions in sponge holobionts.

ABSTRACT:

Background

Sponges are ancient sessile metazoans, which form with their associated microbial symbionts a complex functional unit called a holobiont. Sponges are a rich source of chemical diversity; however, there is limited knowledge of which holobiont members produce certain metabolites and how they may contribute to chemical interactions. To address this issue, we applied non-targeted liquid chromatography tandem mass spectrometry (LC-MS/MS) and gas chromatography mass spectrometry (GC-MS) to either whole sponge tissue or fractionated microbial cells from six different, co-occurring sponge species.

Results

Several metabolites were commonly found or enriched in whole sponge tissue, supporting the notion that sponge cells produce them. These include 2-methylbutyryl-carnitine

SUBMITTER: Zhang S 

PROVIDER: S-EPMC8805237 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature