Variability of adiposity indices and incident heart failure among adults with type 2 diabetes.

ABSTRACT:

Background

It remains unclear how the variability of adiposity indices relates to incident HF. This study evaluated the associations of the variability in several adiposity indices with incident heart failure (HF) in individuals with type 2 diabetes (T2DM).

Methods

We included 4073 participants from the Look AHEAD (Action for Health in Diabetes) study. We assessed variability of body mass index (BMI), waist circumference (WC), and body weight across four annual visits using three variability metrics, the variability independent of the mean (VIM), coefficient of variation (CV), and intraindividual standard deviation (SD). Multivariable Cox regression models were used to generate adjusted hazard ratios (aHR) and 95% confidence intervals (CI) for incident HF.

Results

Ove

SUBMITTER: Kaze AD 

PROVIDER: S-EPMC8805255 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature