Silver Cluster-Porphyrin-Assembled Materials as Advanced Bioprotective Materials for Combating Superbacteria.

ABSTRACT: Superbugs are bacteria that have grown resistant to most antibiotics, seriously threating the health of people. Silver (Ag) nanoparticles are known to exert a wide-spectrum antimicrobial property, yet remains challenging against superbugs. Here, Ag clusters are assembled using porphyrin-based linkers and a novel framework structure (Ag₉ -AgTPyP) is produced, in which nine-nuclearity Ag₉ clusters are uniformly separated by Ag-centered porphyrin units (AgTPyP) in two dimensions, demonstrating open permeant porosity. Ag₉ -AgTPyP eliminates over 99.99999% and 99.999% methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa (P. aeruginosa) within 2 h upon visible-light irradiation, which are superior to a majority of bacteria inactivation ph

SUBMITTER: Cao M 

PROVIDER: S-EPMC8805555 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature