Using dipstick urinalysis to predict development of acute kidney injury in patients with COVID-19.

ABSTRACT:

Background

Acute kidney injury (AKI) is a common complication in patients hospitalized with COVID-19 and may require renal replacement therapy (RRT). Dipstick urinalysis is frequently obtained, but data regarding the prognostic value of hematuria and proteinuria for kidney outcomes is scarce.

Methods

Patients with positive severe acute respiratory syndrome-coronavirus 2 (SARS-CoV2) PCR, who had a urinalysis obtained on admission to one of 20 hospitals, were included. Nested models with degree of hematuria and proteinuria were used to predict AKI and RRT during admission. Presence of Chronic Kidney Disease (CKD) and baseline serum creatinine were added to test improvement in model fit.

Results

Of 5,980 individuals, 829 (13.9%) developed an AKI during admission, and 149

SUBMITTER: McAdams MC 

PROVIDER: S-EPMC8805668 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature