Reactivation of transposable elements following hybridization in fission yeast.

ABSTRACT: Hybridization is thought to reactivate transposable elements (TEs) that were efficiently suppressed in the genomes of the parental hosts. Here, we provide evidence for this "genomic shock hypothesis" in the fission yeast Schizosaccharomyces pombe In this species, two divergent lineages (Sp and Sk) have experienced recent, likely human-induced, hybridization. We used long-read sequencing data to assemble genomes of 37 samples derived from 31 S. pombe strains spanning a wide range of ancestral admixture proportions. A comprehensive TE inventory revealed exclusive presence of long terminal repeat (LTR) retrotransposons. Sequence analysis of active full-length elements, as well as solo LTRs, revealed a complex history of homologous recombination. Population genetic

SUBMITTER: Tusso S 

PROVIDER: S-EPMC8805722 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature