Convalescent plasma may not be an effective treatment for severe and critically ill covid-19 patients: A Systematic Review & Meta-Analysis of Randomized Controlled Trials.

ABSTRACT:

Background

Convalescent plasma treatment for severe and critically ill Corona Virus Disease 2019 (COVID-19) patients remains controversial.

Objective

To evaluate the clinical improvement and mortality risk of convalescent plasma treatment in patients with severe and critically ill COVID-19 patients.

Methods

A literature search was conducted in the electronic databases for the randomized controlled studies about convalescent plasma therapy in severe and critically ill COVID-19 patients. Two reviewers independently extracted relevant data. The primary outcomes were clinical improvement and mortality risk of severe and critically ill COVID-19 patients that were therapied by convalescent plasma.

Results

A total of 14 randomized controlled trials with 4543 patients

SUBMITTER: Yang P 

PROVIDER: S-EPMC8806131 | biostudies-literature | 2022 May-Jun

REPOSITORIES: biostudies-literature