Molecular characterization and the first full sequencing genome of chicken infectious anemia virus (CIAV) in Iran.

ABSTRACT:

Background

The chicken infectious anemia virus (CIAV) is an important pathogen that causes severe immunosuppression in young chickens.

Aims

The study aims to characterize the genotype and full-length sequencing of CIAV strains in Iran.

Methods

First, the collected thymus samples were investigated by conventional PCR for CIAV detection. Second, one of the CIAV positive samples (UT-Zahraee) was chosen for full genome sequencing.

Results

Throughout 2017, we detected 13 CIAVs isolated from 40 broiler flocks of different provinces of Iran. A comparison of the complete sequences of the genome and homologies of the nucleotides revealed that UT-Zahraee had a high similarity with American and Egyptian CIAV isolates. Moreover, VP1 sequence analysis showed that UT-

SUBMITTER: Hosseini H 

PROVIDER: S-EPMC8806177 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature