A Systematic Review of Cost-Effectiveness Analyses for Hepatocellular Carcinoma Treatment.

ABSTRACT:

Background

Hepatocellular carcinoma (HCC) is associated with significant financial burden for patients and payers. The objective of this study was to review economic models to identify, evaluate, and compare cost-effectiveness estimates for HCC treatments.

Methods

A systematic search of the PubMed, Embase, and Cochrane Library databases to identify economic evaluations was performed and studies that modeled treatments for HCC reporting costs and cost effectiveness were included. Risk of bias was assessed qualitatively, considering costing approach, reported study perspective, and funding received. Intervention costs were adjusted to 2021 US dollars for comparison. For studies reporting quality-adjusted life-years (QALYs), we conducted analyses stratified by comparison type t

SUBMITTER: Yuen SC 

PROVIDER: S-EPMC8807829 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature