Project description:The biological fingerprint of environmental adversity may be key to understanding health and disease, as it encompasses the damage induced as well as the compensatory reactions of the organism. Metabolic and hormonal changes may be an informative but incomplete window into the underlying biology. We endeavored to identify objective blood gene expression biomarkers for psychological stress, a subjective sensation with biological roots. To quantify the stress perception at a particular moment in time, we used a simple visual analogue scale for life stress in psychiatric patients, a high risk group. Then, using a stepwise discovery, prioritization, validation, and testing in independent cohorts design, we were successful in identifying gene expression biomarkers that were predictive of high stress states, and of future psychiatric hospitalizations related to stress, more so when personalized by gender and diagnosis.

2019-03-15 | GSE125216 | GEO

Treating pediatric neuromuscular disorders: The future is now.

Project description: Not available

| S-EPMC5900978 | biostudies-literature

PET-MRI Applications and Future Prospects in Psychiatry.

Project description: Not available

| S-EPMC11617601 | biostudies-literature

Subtype-specific cardiomyocytes for precision medicine: Where are we now?

Project description: Not available

| S-EPMC7529810 | biostudies-literature

Towards precision psychiatry: Metabolomics identifies three biological subtypes of depression.

Project description: Not available