Predictors of adverse outcome in the first and second waves of the COVID-19 pandemic: results from a UK centre.

ABSTRACT:

Background/aims

Data concerning differences in demographics/disease severity between the first and second waves of COVID-19 are limited. We aimed to examine prognosis in patients presenting to hospital with COVID-19 amongst different ethnic groups between the first and second waves in the UK.

Methods

In this retrospective cohort study, we included 1763 patients presenting to a regional hospital centre in Leicester (UK) and compared those in the first (n = 956) and second (n = 807) waves. Admission National Early Warning Scores, mechanical ventilation and mortality rate were lower in the second wave compared with the first.

Results

Thirty-day mortality risk in second wave patients was approximately half that of first wave patients [adjusted hazard ratio (

SUBMITTER: Martin CA 

PROVIDER: S-EPMC8808029 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature