Prevalence and Cumulative Risk of Familial Idiopathic Dilated Cardiomyopathy.

ABSTRACT:

Importance

Idiopathic dilated cardiomyopathy (DCM) aggregates in families, and early detection in at-risk family members can provide opportunity to initiate treatment prior to late-phase disease. Most studies have included only White patients, yet Black patients with DCM have higher risk of heart failure-related hospitalization and death.

Objective

To estimate the prevalence of familial DCM among DCM probands and the age-specific cumulative risk of DCM in first-degree relatives across race and ethnicity groups.

Design, setting, and participants

A family-based, cross-sectional study conducted by a multisite consortium of 25 US heart failure programs. Participants included patients with DCM (probands), defined as left ventricular systolic dysfunction and left ventricula

SUBMITTER: Huggins GS 

PROVIDER: S-EPMC8808323 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature