Prognostic impact of tumor location in resected gallbladder cancer: A national cohort analysis.

ABSTRACT:

Background and objectives

Tumor location (peritoneal vs hepatic) has been incorporated in the 8th edition of the American Joint Committee on Cancer Staging system for gallbladder cancer. However, larger studies are needed to confirm the prognostic impact of tumor location.

Methods

Patients with pathologically-confirmed gallbladder cancer with information on primary tumor location were included from the National Cancer Database (2009-2012). We compared patients with hepatic-side tumors to those on the peritoneal side. Survival data were plotted using the Kaplan-Meier method. Prognostic factors were modeled with a multivariate Cox Proportional Hazards Model. Primary outcome was overall survival (OS).

Results

A total of 1251 patients were included. In comparison to patie

SUBMITTER: Lafaro K 

PROVIDER: S-EPMC8808377 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature