Computational model for detector timing effects in Compton-camera based prompt-gamma imaging for proton radiotherapy.

ABSTRACT: This paper describes a realistic simulation of a Compton-camera (CC) based prompt-gamma (PG) imaging system for proton range verification for a range of clinical dose rates, and its comparison to PG measured data with a pre-clinical CC. We used a Monte Carlo plus Detector Effects (MCDE) model to simulate the production of prompt gamma-rays (PG) and their energy depositions in the CC. With Monte Carlo, we simulated PG emission resulting from irradiation of a high density polyethylene phantom with a 150 MeV proton pencil beam at dose rates of 5.0 × 10⁸, 2.6 × 10⁹, and 4.6 × 10⁹ p⁺ s^-1. Realistic detector timing effects (e.g. delayed triggering time, event-coincidence, dead time, etc,) were added in post-processing to allow for flexible c

SUBMITTER: Maggi P 

PROVIDER: S-EPMC8808425 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature