Knee Joint Distraction as Treatment for Osteoarthritis Results in Clinical and Structural Benefit: A Systematic Review and Meta-Analysis of the Limited Number of Studies and Patients Available.

ABSTRACT:

Objective

Knee joint distraction (KJD) is a joint-preserving osteoarthritis treatment that may postpone a total knee arthroplasty (TKA) in younger patients. This systematic review and meta-analysis evaluates short- and long-term clinical benefit and tissue structure changes after KJD.

Design

MEDLINE, EMBASE, and Web of Science were searched for eligible clinical studies evaluating at least one of the primary parameters: WOMAC, VAS-pain, KOOS, EQ5D, radiographic joint space width or MRI cartilage thickness after KJD. Random effects models were applied on all outcome parameters and outcomes were compared with control groups found in the included studies.

Results

Eleven articles reporting on 7 different KJD cohorts with in total 127 patients and 5 control groups with mul

SUBMITTER: Jansen MP 

PROVIDER: S-EPMC8808886 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature