Venous Thrombotic Events in ANCA-Associated Vasculitis: Incidence and Risk Factors.

ABSTRACT:

Background

The incidence of venous thromboembolism (VTE) is increased in ANCA-associated vasculitis (AAV). We assessed the frequency of VTE observed among patients with AAV evaluated at our center and identified risk factors.

Methods

Patients from the Johns Hopkins Vasculitis Center cohort who were evaluated between 1998 and 2018 and had a diagnosis of granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) were eligible for analysis. Baseline demographics and clinical and serologic data were extracted. Univariate and multivariate analyses were performed to identify factors associated with VTE in AAV.

Results

A total of 162 patients with AAV were identified, 105 (65%) with GPA; 22 (14%) of these patients had a recorded VTE with a median time to VTE of

SUBMITTER: Isaacs B 

PROVIDER: S-EPMC8809268 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature