Toroidal topology of population activity in grid cells.

ABSTRACT: The medial entorhinal cortex is part of a neural system for mapping the position of an individual within a physical environment¹. Grid cells, a key component of this system, fire in a characteristic hexagonal pattern of locations², and are organized in modules³ that collectively form a population code for the animal's allocentric position¹. The invariance of the correlation structure of this population code across environments^4,5 and behavioural states^6,7, independent of specific sensory inputs, has pointed to intrinsic, recurrently connected continuous attractor networks (CANs) as a possible substrate of the grid pattern^1,8-11. However, whether grid cell networks show continuous attractor dynamics, and how they i

SUBMITTER: Gardner RJ 

PROVIDER: S-EPMC8810387 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature