The interplay between community and hospital Enterococcus faecium clones within health-care settings: a genomic analysis.

ABSTRACT:

Background

The genomic relationships among Enterococcus faecium isolates are the subject of ongoing research that seeks to clarify the origins of observed lineages and the extent of horizontal gene transfer between them, and to robustly identify links between genotypes and phenotypes. E faecium is considered to form distinct groups-A and B-corresponding to isolates derived from patients who were hospitalised (A) and isolates from humans in the community (B). The additional separation of A into the so-called clades A1 and A2 remains an area of uncertainty. We aimed to investigate the relationships between A1 and non-A1 groups and explore the potential role of non-A1 isolates in shaping the population structure of hospital E faecium.

Methods

We collected s

SUBMITTER: van Hal SJ 

PROVIDER: S-EPMC8810393 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature