Non-Stationary Outcome of Alternating Hemiplegia of Childhood into Adulthood.

ABSTRACT:

Background

Although described as non-progressive, alternating hemiplegia of childhood (AHC) can display a sudden deterioration, anecdotally reported mainly in childhood. Outcome in adulthood is uncertain.

Objectives

Aim of this study is to describe the long-term follow-up of neurological function in adults with AHC.

Methods

Seven adults with AHC were included in this retrospective single-center study. Clinical history and previous investigation data were gathered from the review of medical records. Video-documented neurological examination was performed at the last follow-up visit in four out of the seven reported indivisuals.

Results

Over a median follow-up of 16 years, neurological outcome and trajectories were heterogeneous. All individuals showed new neurol

SUBMITTER: Perulli M 

PROVIDER: S-EPMC8810436 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature