Free-breathing 3D cardiac T₁ mapping with transmit B₁ correction at 3T.

ABSTRACT:

Purpose

To develop a cardiac T₁ mapping method for free-breathing 3D T₁ mapping of the whole heart at 3 T with transmit B₁ ( B1+ ) correction.

Methods

A free-breathing, electrocardiogram-gated inversion-recovery sequence with spoiled gradient-echo readout was developed and optimized for cardiac T₁ mapping at 3 T. High-frame-rate dynamic images were reconstructed from sparse (k,t)-space data acquired along a stack-of-stars trajectory using a subspace-based method for accelerated imaging. Joint T₁ and flip-angle estimation was performed in T₁ mapping to improve its robustness to B1+ inhomogeneity. Subject-specific timing of data acquisition was used in the estimation to account for natural heart-rate variations

SUBMITTER: Han PK 

PROVIDER: S-EPMC8810588 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature