Optimization of pseudo-continuous arterial spin labeling using off-resonance compensation strategies at 7T.

ABSTRACT:

Purpose

The sensitivity of pseudo-continuous arterial spin labeling (PCASL) to off-resonance effects (ΔB₀ ) is a major limitation at ultra-high field (≥7T). The aim of this study was to assess the effectiveness of different PCASL ΔB₀ compensation methods at 7T and measure the labeling efficiency with off-resonance correction.

Theory and methods

Phase offset errors induced by ΔB₀ at the feeding arteries can be compensated by adding an extra radiofrequency (RF) phase increment and transverse gradient blips into the PCASL RF pulse train. The effectiveness of an average field correction (AVGcor), a vessel-specific field-map-based correction (FMcor) and a vessel-specific prescan-based correction (PScor) were compared at 7T. After correction, the P

SUBMITTER: Saib G 

PROVIDER: S-EPMC8810716 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature