Prenatal PM_2.5 exposure and infant temperament at age 6 months: Sensitive windows and sex-specific associations.

ABSTRACT:

Background

Prenatal exposure to fine particulate matter with a diameter of ≤2.5 μm (PM_2.5) has been linked to adverse neurodevelopmental outcomes in later childhood, while research on early infant behavior remains sparse.

Objectives

We examined associations between prenatal PM_2.5 exposure and infant negative affectivity, a stable temperamental trait associated with longer-term behavioral and mental health outcomes. We also examined sex-specific effects.

Methods

Analyses included 559 mother-infant pairs enrolled in the PRogramming of Intergenerational Stress Mechanisms (PRISM) cohort. Daily PM_2.5 exposure based on geocoded residential address during pregnancy was estimated using a satellite-based spatiotemporal model. Domains of negativ

SUBMITTER: Rahman F 

PROVIDER: S-EPMC8810739 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature