Women with a history of preeclampsia have preserved sensory nerve-mediated dilatation in the cutaneous microvasculature.

ABSTRACT:

New findings

What is the central question of this study? Are sensory nerve-mediated vasodilatation and the NO-dependent contribution to that response attenuated in the cutaneous microvasculature of women who have had preeclampsia? What is the main finding and its importance? Women who have had preeclampsia demonstrate attenuated microvascular endothelium-dependent dilatation compared to women with a history of uncomplicated pregnancy. However, there are no differences in sensory nerve-mediated vasodilatation between groups. This suggests that the neurogenic response is not altered following preeclampsia, and that the NO-dependent vasodilatation of the neurogenic response is not related to endothelium-dependent NO-mediated dilatation in these women.

Abstract

Women who have ha

SUBMITTER: Pyevich M 

PROVIDER: S-EPMC8810741 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature