Photothermal inactivation of universal viral particles by localized surface plasmon resonance mediated heating filter membrane.

ABSTRACT: This study introduces localized surface plasmon resonance (L-SPR) mediated heating filter membrane (HFM) for inactivating universal viral particles by using the photothermal effect of plasmonic metal nanoparticles (NPs). Plasmonic metal NPs were coated onto filter membrane via a conventional spray-coating method. The surface temperature of the HFM could be controlled to approximately 40-60 °C at room temperature, owing to the photothermal effect of the gold (Au) NPs coated on them, under irradiation by visible light-emitting diodes. Due to the photothermal effect of the HFMs, the virus titer of H1Npdm09 was reduced by > 99.9%, the full inactivation time being < 10 min, confirming the 50% tissue culture infective dose (TCID₅₀) assay. Crystal violet staining showed that the infect

SUBMITTER: Yoo S 

PROVIDER: S-EPMC8810778 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature