Seasonality of cognitive function in the general population: the Rotterdam Study.

ABSTRACT: Seasonal variation in cognitive function and underlying cerebral hemodynamics in humans has been suggested, but not consistently shown in previous studies. We assessed cognitive function in 10,276 participants from the population-based Rotterdam Study, aged 45 years and older without dementia, at baseline and at subsequent visits between 1999 and 2016. Seasonality of five cognitive test scores and of a summary measure of global cognition were determined, as well as of brain perfusion. Using linkage with medical records, we also examined whether a seasonal variation was present in clinical diagnoses of dementia. We found a seasonal variation of global cognition (0.05 standard deviations [95% confidence interval: 0.02-0.08]), the Stroop reading task, the Purdue Pegboard test, and of the dela

SUBMITTER: Mooldijk SS 

PROVIDER: S-EPMC8810929 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature