Undifferentiated Connective Tissue Disease in Pregnancy: A Topic Yet to be Explored.

ABSTRACT: Undifferentiated connective tissue disease (UCTD) is characterized by signs and symptoms suggestive of a connective tissue disease (CTD), but not fulfilling criteria for a specific CTD. Although UCTD is probably the most common rheumatic disease diagnosed in pregnant women, data about disease course during pregnancy and perinatal outcomes are very limited. Compared to other CTDs, UCTD seems to have milder clinical manifestations in pregnancy. Its natural history is related to disease activity at conception. In fact, if the disease is in a state of remission or minimal activity at conception, pregnancy outcomes are generally good. On the contrary, patients who become pregnant in a moment of high disease activity and/or who have multiple antibodies positivity show an increased risk of diseas

SUBMITTER: Serena C 

PROVIDER: S-EPMC8811283 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature