Cysteine cathepsin C: a novel potential biomarker for the diagnosis and prognosis of glioma.

ABSTRACT:

Background

Cysteine cathepsin C encoded by the CTSC gene is an important member of the cysteine cathepsin family that plays a key role regulation of many types of tumors. However, whether CTSC is involved in the pathological process of glioma has not yet been reported. We comprehensively analyzed data from multiple databases and for the first time revealed a role and specific mechanism of action of CTSC in glioma, identifying it as a novel and efficient biomarker for the diagnosis and treatment of this brain tumor.

Methods

The expression of CTSC in glioma and its relationship with clinical characteristics and prognosis of patients with glioma were analyzed at different levels by using clinical sample information from several databases. CTSC expression levels in glioma and no

SUBMITTER: Cheng X 

PROVIDER: S-EPMC8812029 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature