Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome.

ABSTRACT:

Background

Yoghurt contains live bacteria that could contribute via modulation of the gut microbiota to its reported beneficial effects such as reduced body weight gain and lower incidence of type 2 diabetes. To date, the association between yoghurt consumption and the composition of the gut microbiota is underexplored. Here we used clinical variables, metabolomics, 16S rRNA and shotgun metagenomic sequencing data collected on over 1000 predominantly female UK twins to define the link between the gut microbiota and yoghurt-associated health benefits.

Results

According to food frequency questionnaires (FFQ), 73% of subjects consumed yoghurt. Consumers presented a healthier diet pattern (healthy eating index: beta = 2.17 ± 0.34; P = 2.72x10^-10) and improved metaboli

SUBMITTER: Le Roy CI 

PROVIDER: S-EPMC8812230 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature