Correlation between brain tissue oxygen tension and regional cerebral oximetry in uninjured human brain under conditions of changing ventilation strategy.

ABSTRACT: Controversy surrounds regional cerebral oximetry (rSO₂) because extracranial contamination and unmeasured changes in cerebral arterial:venous ratio confound readings. Correlation of rSO₂ with brain tissue oxygen (PbrO₂), a "gold standard" for cerebral oxygenation, could help resolve this controversy but PbrO₂ measurement is highly invasive. This was a prospective cohort study. The primary aim was to evaluate correlation between PbrO₂ and rSO₂ and the secondary aim was to investigate the relationship between changing ventilation regimens and measurement of PbrO₂ and rSO₂. Patients scheduled for elective removal of cerebral metastases were anesthetized with propofol and remifentanil, targeted to a BIS ran

SUBMITTER: Picton P 

PROVIDER: S-EPMC8812359 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature