Metabolomics in endometriosis: challenges and perspectives for future studies.

ABSTRACT: Endometriosis is a complex disease characterized by inflammation and the growth of endometrial- like glands and stroma outside the uterine cavity. The pathophysiology of endometriosis is not entirely understood, however, with a prevalence of ~10% of women in their reproductive years, the disease symptoms significantly affect the quality of life of millions of women globally. Metabolomic studies have previously identified specific metabolites that could be a signature of endometriosis. This approach could potentially be used as a non-invasive tool for early diagnosis and provide a better understanding of endometriosis pathophysiology. This review aims to provide insight as to how endometriosis affects the metabolome by reviewing different studies that have used this approach to design follo

SUBMITTER: Ortiz CN 

PROVIDER: S-EPMC8812441 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature