Late responses in the anterior insula reflect the cognitive component of pain: evidence of nonpain processing.

ABSTRACT:

Introduction

Pain is a complex experience influenced by sensory and psychological factors. The insula is considered to be a core part of the pain network in the brain. Previous studies have suggested a relationship between the posterior insula (PI) and sensory processing, and between the anterior insula (AI) and cognitive-affective factors.

Objectives

Our aim was to distinguish sensory and cognitive responses in pain-related insular activities.

Methods

We recorded spatiotemporal insular activation patterns of healthy participants (n = 20) during pain or tactile processing with painful or nonpainful movie stimuli, using a magnetoencephalography. We compared the peak latency between PI and AI activities in each stimulus condition, and between pain and tactile processing

SUBMITTER: Taniguchi N 

PROVIDER: S-EPMC8812601 | biostudies-literature | 2022 Mar-Apr

REPOSITORIES: biostudies-literature