Quantitative determination of pulmonary emphysema in follow-up LD-CTs of patients with COVID-19 infection.

ABSTRACT:

Purpose

To evaluate the association between the coronavirus disease 2019 (COVID-19) and post-inflammatory emphysematous lung alterations on follow-up low-dose CT scans.

Methods

Consecutive patients with proven COVID-19 infection and a follow-up CT were retrospectively reviewed. The severity of pulmonary involvement was classified as mild, moderate and severe. Total lung volume, emphysema volume and the ratio of emphysema/-to-lung volume were quantified semi-automatically and compared inter-individually between initial and follow-up CT and to a control group of healthy, age- and sex-matched patients. Lung density was further assessed by drawing circular regions of interest (ROIs) into non-affected regions of the upper lobes.

Results

A total of 32 individuals (mean age:

SUBMITTER: Celik E 

PROVIDER: S-EPMC8812925 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature