Inter- and intradialytic fluid volume changes and vascular stiffness parameters in patients on hemodialysis.

ABSTRACT:

Background

Whether fluid overload is associated with vascular stiffness parameters in hemodialysis (HD) patients has not been fully elucidated. We hypothesized that interdialytic fluid accumulation increases vascular stiffness parameters, which improves with intradialytic ultrafiltration.

Methods

Fluid overload and vascular stiffness parameters were assessed in 39 HD patients (20 with and 19 without fluid overload) and compared to 26 healthy controls. Fluid status was assessed 15 minutes before the mid-week HD session by bio-impedance spectroscopy. Following this, ambulatory pulse wave velocity (PWV) and augmentation index (AIx) were measured for 24 hours before another mid-week HD session and then for 5 hours starting 30 minutes before and ending 30 minutes after the sessio

SUBMITTER: Lafta A 

PROVIDER: S-EPMC8812974 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature