Abnormal Static and Dynamic Functional Connectivity in Left and Right Temporal Lobe Epilepsy.

ABSTRACT:

Objective

Temporal lobe epilepsy (TLE) can be conceptualized as a network disease. However, the network characteristics in lateralization remain controversial.

Methods

In this study, resting-state functional MRI scans were acquired from 53 TLE patients [22 with left-side TLE (LTLE) and 31 with right-side TLE (RTLE)] and 37 matched healthy controls. We focused on the characteristics of static and dynamic functional connectivity, including static connectivity patterns and topological properties, as well as temporal properties of the dynamic connectivity state and the variability of the dynamic connectivity and network topological organization. Correlation analyses were conducted between abnormal static and dynamic properties and cognitive performances.

Results

The stati

SUBMITTER: Pang X 

PROVIDER: S-EPMC8813030 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature