Antioxidant, anti-inflammatory and immunomodulatory roles of vitamins in COVID-19 therapy.

ABSTRACT: oxidative stress is caused by an abundant generation of reactive oxygen species, associated to a diminished capacity of the endogenous systems of the organism to counteract them. Activation of pro-oxidative pathways and boosting of inflammatory cytokines are always encountered in viral infections, including SARS-CoV-2. So, the importance of counteracting cytokine storm in COVID-19 pathology is highly important, to hamper the immunogenic damage of the endothelium and alveolar membranes. Antioxidants prevent oxidative processes, by impeding radical species generation. It has been proved that vitamin intake lowers oxidative stress markers, alleviates cytokine storm and has a potential role in reducing disease severity, by lowering pro-inflammatory cytokines, hampering hyperinflammation and or

SUBMITTER: Pisoschi AM 

PROVIDER: S-EPMC8813210 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature