[High burden of disease in patients with ANCA-associated vasculitis : A claims data study in Germany].

ABSTRACT:

Background & objectives

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) represents a group of rare chronic autoimmune diseases characterized by recurrent systemic inflammation provoking multiple morbidities. AAV patients suffer from various organ manifestations and treatment-related severe adverse effects. This retrospective study investigated the concrete burden of AAV disease on patients in Germany.

Methods

Based on anonymized longitudinal German statutory health insurance (SHI) claims data from the years 2011-2016, a representative cohort of approximately 3 million insured persons was used to identify patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), and selected clinical aspects were systematically assessed.

SUBMITTER: Haller HG 

PROVIDER: S-EPMC8813869 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature