Altered Neurovascular Coupling in Unilateral Pulsatile Tinnitus.

ABSTRACT:

Objective

Altered cerebral blood flow (CBF) and regional homogeneity (ReHo) have been reported in pulsatile tinnitus (PT) patients. We aimed to explore regional neurovascular coupling changes in PT patients.

Materials and methods

Twenty-four right PT patients and 25 sex- and age-matched normal controls were included in this study. All subjects received arterial spin labeling imaging to measure CBF and functional MRI to compute ReHo. CBF/ReHo ratio was used to assess regional neurovascular coupling between the two groups. We also analyzed the correlation between CBF/ReHo ratio and clinical data from the PT patients.

Results

PT patients exhibited increased CBF/ReHo ratio in left middle temporal gyrus and right angular gyrus than normal controls, and no decreased CBF/ReH

SUBMITTER: Li X 

PROVIDER: S-EPMC8815060 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature