Patients' experiences treated with open-label placebo versus double-blind placebo: a mixed methods qualitative study.

ABSTRACT:

Background

There is increasing evidence suggesting that open-label placebo (OLP) is an effective treatment for several medical conditions defined by self-report. However, little is known about patients' experiences with OLP, and no studies have directly compared patients' experiences in double-blind placebo (DBP) conditions.

Methods

This study was nested in a large randomized-controlled trial comparing the effects of OLP and DBP treatments in individuals with irritable bowel syndrome (IBS). We randomly selected 33 participants for interviews concerning their experiences in the parent trial. The data were qualitatively analyzed using an iterative immersion/crystallization approach. We then compared the qualitative interview data to the quantitative IBS severity data assessed

SUBMITTER: Haas JW 

PROVIDER: S-EPMC8815135 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature