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Microelectrode Arrays, Dihydroxylation, and the Development of an Orthogonal Safety-Catch Linker.


ABSTRACT: Construction of larger molecular libraries on an addressable microelectrode array requires a method for recovering and characterizing molecules from the surface of any electrode in the array. This method must be orthogonal to the synthetic strategies needed to build the array. We report here a method for achieving this goal that employs the site-selective dihydroxylation reaction of a simple olefin.

SUBMITTER: Yeh NH 

PROVIDER: S-EPMC8815274 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature

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Microelectrode Arrays, Dihydroxylation, and the Development of an Orthogonal Safety-Catch Linker.

Yeh Nai-Hua NH   Krueger Ruby R   Moeller Kevin D KD  

Organic letters 20210629 14


Construction of larger molecular libraries on an addressable microelectrode array requires a method for recovering and characterizing molecules from the surface of any electrode in the array. This method must be orthogonal to the synthetic strategies needed to build the array. We report here a method for achieving this goal that employs the site-selective dihydroxylation reaction of a simple olefin. ...[more]

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