Histopathologic and Clinical Features in Patients with Diabetes and Kidney Disease.

ABSTRACT:

Background

The discovery of nondiabetic kidney disease (NDKD) in an individual patient with diabetes may have significant treatment implications. Extensive histopathologic data in this population are lacking, but they may provide insights into the complex pathogenesis of diabetic nephropathy (DN) and reveal specific phenotypes for the development of targeted therapies. This study seeks to elucidate the clinical and laboratory parameters associated with the spectrum of kidney histopathologic features in patients with diabetes.

Methods

This study is a retrospective analysis of 399 kidney biopsies assessed from 2014 to 2016 at the University of Washington among patients with diabetes. More comprehensive clinical data were evaluated in a subset of 79 participants.

Results

SUBMITTER: Sanghavi SF 

PROVIDER: S-EPMC8815499 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature