A Model To Estimate Glucose Absorption in Peritoneal Dialysis: A Pilot Study.

ABSTRACT:

Background

Glucose absorption in patients on peritoneal dialysis (PD) may contribute to adverse metabolic effects. Previous studies on glucose absorption were done on patients on continuous ambulatory PD, with a long dwell time. However, the growing majority of contemporary patients on PD perform automated PD with a short dwell time. Moreover, membrane characteristics and dwell time determine small-solute transport across the peritoneal membrane.

Methods

In our pilot study, we used data from the peritoneal equilibration test (PET) to develop a model to estimate glucose absorption. In six randomly selected patients on PD, we calculated actual glucose absorption from directly measuring effluent glucose concentration. We then used the R programming language to create a nonlinea

SUBMITTER: Kotla SK 

PROVIDER: S-EPMC8815531 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature