The Impact of Antimicrobial Stewardship in Children in Low- and Middle-income Countries: A Systematic Review.

ABSTRACT:

Background

Antimicrobial stewardship (AMS) is central to the World Health Organisation Global Action Plan against antimicrobial resistance (AMR). If antibiotics are used without restraint, morbidity and mortality from AMR will continue to increase. In resource-rich settings, AMS can safely reduce antibiotic consumption. However, for children in low- and middle-income countries (LMIC), the impact of different AMS interventions is unknown.

Aim

To determine the impact of different AMS interventions on antibiotic use and clinical and microbiologic outcomes in children in LMIC.

Methods

MEDLINE, Embase and PubMed were searched for studies of AMS interventions in pediatric population in LMIC settings. Controlled trials, controlled before-and-after studies and interrupted tim

SUBMITTER: Abo YN 

PROVIDER: S-EPMC8815847 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature