Quantitative analysis of visual codewords of a protein distance matrix.

ABSTRACT: 3D protein structures can be analyzed using a distance matrix calculated as the pairwise distance between all Cα atoms in the protein model. Although researchers have efficiently used distance matrices to classify proteins and find homologous proteins, much less work has been done on quantitative analysis of distance matrix features. Therefore, the distance matrix was analyzed as gray scale image using KAZE feature extractor algorithm with Bag of Visual Words model. In this study, each protein was represented as a histogram of visual codewords. The analysis showed that a very small number of codewords (~1%) have a high relative frequency (> 0.25) and that the majority of codewords have a relative frequency around 0.05. We have also shown that there is a relationship between the frequency o

SUBMITTER: Praznikar J 

PROVIDER: S-EPMC8815937 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature