Pericoronary fat attenuation index in computed tomography angiography is associated with mortality in end-stage renal disease.

ABSTRACT:

Background

An increased pericoronary fat attenuation index (FAI) on computed tomography angiography (CTA) is associated with increased all-cause and cardiac mortality in the general population. However, the ability of pericoronary FAI to predict long-term outcomes in chronic kidney disease (CKD) patients is unknown.

Methods

In this single-center retrospective longitudinal cohort study, we assessed the utility of CTA-based pericoronary FAI measurement to predict mortality of CKD patients, including those with end-stage renal disease (ESRD). Mapping and analysis of pericoronary FAI involved three major proximal coronary arteries. The prognostic value of pericoronary FAI for long-term mortality was assessed with multivariable Cox regression models.

Results

Among 268 CKD

SUBMITTER: Cho NJ 

PROVIDER: S-EPMC8816413 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature